Versican
Gene Symbol   VCAN Chromosome Locus   5q14.3
 
  Alternate Names    
     
 
Chondroitin sulfate proteoglycan core protein 2; PG-M; Glial hyaluronate binding protein
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma DNA microarray
Increased
6.1
Jin et al. 2006
Invasive ductal adenocarcinoma DNA microarray
Increased
12.3
Johnson et al. 2006
Invasive ductal adenocarcinoma DNA microarray
Increased
5
Iacobuzio-Donahue et al. 2002
Invasive ductal adenocarcinoma DNA microarray
Increased
2.8
Crnogorac-Jurcevic et al. 2001
Invasive ductal adenocarcinoma DNA microarray
Increased
11.9
Tan et al. 2003
Invasive ductal adenocarcinoma DNA microarray
Increased
4.8
Lowe et al. 2007
Invasive ductal adenocarcinoma DNA microarray
Increased
20.6
Friess et al. 2003
Invasive ductal adenocarcinoma DNA microarray
Increased
5
Nakamura et al. 2004
Invasive ductal adenocarcinoma RT-PCR
Increased
60
Koninger et al. 2004
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
MiaPaCa2 RT-PCR
Increased
Koninger et al. 2004
Capan1 RT-PCR
Increased
Koninger et al. 2004
Colo357 RT-PCR
Increased
Koninger et al. 2004
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma ICAT
Increased
2.7
Chen et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Koninger et al.
Invasive ductal adenocarcinoma Label free quantitation, Mass spectrometry
Increased
20.8
Pan et al. 2011
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
RNA DNA microarray
Increased
15.2
Friess et al.
Protein ICAT
Increased
3
Chen et al.
Protein Label free quantitation, Mass spectrometry
Increased
8.2
Pan et al. 2011
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."