Pancreatic Cancer Database

Versican

Gene Symbol

VCAN

Chromosome Locus

5q14.3

Alternate Names

Chondroitin sulfate proteoglycan core protein 2; PG-M; Glial hyaluronate binding protein

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Increased	6.1	Jin et al. 2006
Invasive ductal adenocarcinoma	DNA microarray	Increased	12.3	Johnson et al. 2006
Invasive ductal adenocarcinoma	DNA microarray	Increased	5	Iacobuzio-Donahue et al. 2002
Invasive ductal adenocarcinoma	DNA microarray	Increased	2.8	Crnogorac-Jurcevic et al. 2001
Invasive ductal adenocarcinoma	DNA microarray	Increased	11.9	Tan et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	4.8	Lowe et al. 2007
Invasive ductal adenocarcinoma	DNA microarray	Increased	20.6	Friess et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	5	Nakamura et al. 2004
Invasive ductal adenocarcinoma	RT-PCR	Increased	60	Koninger et al. 2004

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	ICAT	Increased	2.7	Chen et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Koninger et al.
Invasive ductal adenocarcinoma	Label free quantitation, Mass spectrometry	Increased	20.8	Pan et al. 2011

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
RNA	DNA microarray	Increased	15.2	Friess et al.
Protein	ICAT	Increased	3	Chen et al.
Protein	Label free quantitation, Mass spectrometry	Increased	8.2	Pan et al. 2011

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
00340	1462	118661	HGNC:2464