Tight junction protein 1 (zona occludens 1)
Gene Symbol   TJP1 Chromosome Locus   15q13
 
  Alternate Names    
     
 
Zona occludens 1; Zonula occludens 1; ZO1
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma Northern blot
Increased
6
Kleeff et al. 2001
PanIN-3 DNA microarray
Increased
2.3
Buchholz et al. 2005
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
ASPC-1 Northern blot
Increased
Kleeff et al. 2001
CAPAN-1 Northern blot
Increased
Kleeff et al. 2001
COLO-357 Northern blot
Increased
Kleeff et al. 2001
T3M4 Northern blot
Increased
Kleeff et al. 2001
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
ASPC-1 Western blot
Increased
Kleeff et al. 2001
CAPAN-1 Western blot
Increased
Kleeff et al. 2001
COLO-357 Western blot
Increased
Kleeff et al. 2001
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
RNA Northern blot
Increased
2.4
 Kleeff et al.
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."