Plasminogen activator, tissue
Gene Symbol   PLAT Chromosome Locus   8p12
 
  Alternate Names    
     
 
Plasminogen activator tissue type isoform 3; Plasminogen activator tissue type isoform 1 preproprotein; Plasminogen activator, tissue type
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma DNA microarray
Increased
12.5
Friess et al. 2003
Invasive ductal adenocarcinoma SAGE
Increased
Miller et al. 2002
Invasive ductal adenocarcinoma DNA microarray
Increased
6.7
Laurell et al. 2006
Invasive ductal adenocarcinoma DNA microarray
Increased
6.1
Lowe et al. 2007
Invasive ductal adenocarcinoma RT-PCR
Increased
Laurell et al. 2006
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
IMIM-PC-l Northern blot
Increased
Paciucci et al. 1996
IMIM-PC-2 Northern blot
Increased
Paciucci et al. 1996
RWP-1 Northern blot
Increased
Paciucci et al. 1998
Capan-1 Northern blot
Increased
Paciucci et al. 1998
SK-PC-1 Northern blot
Increased
Paciucci et al. 1998
MZ-PC-2 Northern blot
Increased
Paciucci et al. 1998
IMIM-PC-2 Northern blot
Increased
Paciucci et al. 1998
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Paciucci et al.
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
RWP-1 ELISA
Increased
Paciucci et al. 1998
Capan-1 ELISA
Increased
Paciucci et al. 1998
SK-PC-1 ELISA
Increased
Paciucci et al. 1998
MZ-PC-2 ELISA
Increased
Paciucci et al. 1998
IMIM-PC-2 ELISA
Increased
Paciucci et al. 1998
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
RNA DNA microarray
Increased
15
Friess et al.
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."