Pancreatic Cancer Database

Cathepsin E

Gene Symbol

CTSE

Chromosome Locus

1q31

Alternate Names

Cathepsin E isoform b preproprotein; Cathepsin E isoform a preproprotein; Erythrocyte membrane aspartic proteinase

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Intraductal papillary mucinous neoplasms	DNA microarray	Increased	6.6	Sato et al. 2004
Intraductal papillary mucinous neoplasms	DNA microarray	Increased	8.4	Terris et al. 2002
Invasive ductal adenocarcinoma	DNA microarray	Increased	67.9	Pfeffer et al. 2004
Invasive ductal adenocarcinoma	SAGE	Increased		Terris et al. 2002
Invasive ductal adenocarcinoma	DNA microarray	Increased	7.7	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	12.1	Johnson et al. 2006
Invasive ductal adenocarcinoma	DNA microarray	Increased	37.5	Friess et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	7.8	Lowe et al. 2007
Invasive ductal adenocarcinoma	DNA microarray	Increased	2.4	Buchholz et al. 2005
Mucinous cystic neoplasms	DNA microarray	Increased	6.6	Fukushima et al. 2004
PanIN-1A	DNA microarray	Increased	16.2	Prasad et al. 2005
PanIN-1B	DNA microarray	Increased	16.2	Prasad et al. 2005
PanIN-2	DNA microarray	Increased	16.2	Prasad et al. 2005

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Buchholz et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
RNA	DNA microarray	Increased	2	Friess et al.

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
00294	1510	116890	HGNC:2530