Collagen, type I, alpha 2
Gene Symbol   COL1A2 Chromosome Locus   7q22.1
 
  Alternate Names    
     
 
Collagen of skin, tendon, and bone, alpha 2 chain; Collagen I, alpha-2 polypeptide
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma DNA microarray
Increased
8.8
Iacobuzio-Donahue et al. 2002
Invasive ductal adenocarcinoma DNA microarray
Increased
4.9
Lowe et al. 2007
Invasive ductal adenocarcinoma DNA microarray
Increased
37.2
Friess et al. 2003
Invasive ductal adenocarcinoma DNA microarray
Increased
6.3
Johnson et al. 2006
Invasive ductal adenocarcinoma DNA microarray
Increased
12.5
Tan et al. 2003
Invasive ductal adenocarcinoma DNA microarray
Increased
5
Nakamura et al. 2004
Invasive ductal adenocarcinoma SAGE
Increased
Hustinx et al. 2004
Invasive ductal adenocarcinoma DNA microarray
Increased
11.6
Jin et al. 2006
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma Label free quantitation, Mass spectrometry
Increased
6.6
 Pan et al. 2011
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
RNA DNA microarray
Increased
29.3
 Friess et al.
RNA DNA microarray
Increased
2
 Binkley et al. 2004
Protein Label free quantitation, Mass spectrometry
Increased
5.4
 Pan et al. 2011
Protein Label free quantitation, Mass spectrometry
Increased
8.3
 Pan et al. 2011
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."