Pancreatic Cancer Database

Chemokine (C-C motif) ligand 2

Gene Symbol

CCL2

Chromosome Locus

17q11.2-q12

Alternate Names

SCYA2; MCP1; Small inducible cytokine A2

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	In situ hybridization	Increased		Monti et al. 2003

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
Capan-1	Northern blot	Increased		Monti et al. 2003
Panc-1	Northern blot	Increased		Monti et al. 2003
Hs 766T	Northern blot	Increased		Monti et al. 2003
SU 8686	Northern blot	Increased		Monti et al. 2003
PT45P1	Northern blot	Increased		Monti et al. 2003
PC13	Northern blot	Increased		Monti et al. 2003

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	ELISA	Increased		Monti et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Monti et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
Capan-1	ELISA	Increased		Monti et al. 2003
Panc-1	ELISA	Increased		Monti et al. 2003
Hs 766T	ELISA	Increased		Monti et al. 2003
SU 8686	ELISA	Increased		Monti et al. 2003
PT45P1	ELISA	Increased		Monti et al. 2003
PC13	ELISA	Increased		Monti et al. 2003
Panc1	SILAC	Increased	20	Gronborg et al. 2005

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
RNA	In situ hybridization	Increased		Saurer et al.
Protein	Other assays	Increased		Zeh et al.
RNA	DNA microarray	Increased	24	Rogers et al. 2006

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

-

Secreted

-

Body Fluid

-

External Links

HPRD	Entrez Gene	OMIM	HGNC
01149	6347	158105	HGNC:10618

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."