Pancreatic Cancer Database

Baculoviral IAP repeat-containing 3

Gene Symbol

BIRC3

Chromosome Locus

11q22

Alternate Names

Apoptosis inhibitor 2; cIAP2; TNFR2-TRAF signaling complex protein 1

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Increased	11.5	Friess et al. 2003
Invasive ductal adenocarcinoma	RT-PCR	Increased	5	Lopes et al. 2007
Invasive ductal adenocarcinoma	In situ hybridization	Increased		Lopes et al. 2007
Invasive ductal adenocarcinoma	DNA microarray	Increased	7.5	Iacobuzio-Donahue et al. 2002
Invasive ductal adenocarcinoma	RT-PCR	Increased	2.4	Esposito et al. 2006

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Lopes et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Esposito et al.
Pancreatic intraepithelial neoplasia	Immunohistochemistry	Increased		Esposito et al.
Microcystic serous cystadenoma	Immunohistochemistry	Increased		Esposito et al.
Intraductal papillary mucinous neoplasms	Immunohistochemistry	Increased		Esposito et al.
Other	Immunohistochemistry	Increased		Esposito et al.
Pancreatic intraepithelial neoplasia (PanIN)	Immunohistochemistry	Increased		Esposito et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Esposito et al.
Serous cystadenocarcinoma	Immunohistochemistry	Increased		Esposito et al.

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
RNA	RT-PCR	Increased	1.9	Esposito et al.

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
03426	330	601721	HGNC:591