Pancreatic Cancer Database

S100 calcium-binding protein A2

Gene Symbol

S100A2

Chromosome Locus

1q21

Alternate Names

S 100L protein; CAN19

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma	RT-PCR	Increased		Ohuchida et al. 2007
Pancreatic intraepithelial neoplasia (PanIN)	RT-PCR	Increased		Ohuchida et al. 2007
Invasive ductal adenocarcinoma	RT-PCR	Increased		Ohuchida et al. 2007
Invasive ductal adenocarcinoma	DNA microarray	Increased	24.3	Friess et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	8.5	Lowe et al. 2007
Invasive ductal adenocarcinoma	RT-PCR	Increased		Ohuchida et al. 2005
Invasive ductal adenocarcinoma	DNA microarray	Increased	5.8	Iacobuzio-Donahue et al. 2003

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma	Immunohistochemistry	Increased		Ohuchida et al.
Pancreatic intraepithelial neoplasia (PanIN)	Immunohistochemistry	Increased		Ohuchida et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Ohuchida et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Karanjawala et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
PANC-1	SILAC, Tandem mass spectrometry	Decreased		Gronborg et al.

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
RNA	DNA microarray	Increased	2.4	Friess et al.

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

16215274

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
01508	6273	176993	HGNC:10492