Pancreatic Cancer Database

Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

Gene Symbol

ITGA3

Chromosome Locus

17q21.33

Alternate Names

CD49C; Very late activation protein 3 receptor, alpha 3 subunit; Galactoprotein B3

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Decreased	5	Nakamura et al.
Invasive ductal adenocarcinoma	DNA microarray	Increased	3.2	Lowe et al. 2007
Invasive ductal adenocarcinoma	DNA microarray	Increased	2.4	Laurell et al. 2006
Invasive ductal adenocarcinoma	DNA microarray	Increased	5.6	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	3	Logsdon et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	3.1	Van et al. 2012

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Gesierich et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
Protein	Immunohistochemistry	Increased		Gesierich et al.

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
05431	3675	605025	HGNC:6139