Dual specificity phosphatase 1
Gene Symbol   DUSP1 Chromosome Locus   5q34
 
  Alternate Names    
     
 
Protein tyrosine phosphatase nonreceptor, type10; PTPN10; CL100
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma DNA microarray
Decreased
5
Nakamura et al.
Intraductal papillary mucinous neoplasms DNA microarray
Increased
5
Terris et al. 2002
Invasive ductal adenocarcinoma Northern blot
Increased
8.1
Liao et al. 2003
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
PanIN-1A Immunohistochemistry
Increased
Liao et al.
PanIN-1B Immunohistochemistry
Increased
Liao et al.
PanIN-2 Immunohistochemistry
Increased
Liao et al.
PanIN-3 Immunohistochemistry
Increased
Liao et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Liao et al.
Invasive ductal adenocarcinoma Western blot
Increased
Liao et al.
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
RNA Northern blot
Increased
6.2
Liao et al.
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."