Pancreatic Cancer Database

Lipocalin 2

Gene Symbol

LCN2

Chromosome Locus

9q34

Alternate Names

Neutrophil gelatinase associated lipocalin; Neutrophil gelatinase B associated lipocalin; Lipocalin 24P3

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	RT-PCR	Increased		Moniaux et al.
Intraductal papillary mucinous neoplasms	RT-PCR	Increased		Sato et al. 2004
Intraductal papillary mucinous neoplasms	DNA microarray	Increased	9	Sato et al. 2004
Intraductal papillary mucinous neoplasms	DNA microarray	Increased	18.6	Terris et al. 2002
Invasive ductal adenocarcinoma	RT-PCR	Increased		Laurell et al. 2006
Invasive ductal adenocarcinoma	DNA microarray	Increased	3.4	Laurell et al. 2006
Invasive ductal adenocarcinoma	SAGE	Increased		Hustinx et al. 2004
Invasive ductal adenocarcinoma	DNA microarray	Increased	5.6	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	6.4	Lowe et al. 2007
Invasive ductal adenocarcinoma	DNA microarray	Increased	3	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	SAGE	Increased		Terris et al. 2002
Invasive ductal adenocarcinoma	DNA microarray	Increased	8.9	Iacobuzio-Donahue et al. 2002
Pancreatic ductal adenocarcinoma	qPCR	Decreased		Leung et al. 2012

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Tong et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Moniaux et al.
PanIN-1, PanIN-2, PanIN-3	Immunohistochemistry	Increased		Moniaux et al.
Invasive ductal adenocarcinoma	ELISA	Increased		Moniaux et al.
Intraductal papillary mucinous neoplasms	Immunohistochemistry	Increased		Terris et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Terris et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Laurell et al.
Pancreatic ductal adenocarcinoma	Western blot	Decreased		Leung et al. 2012
Pancreatic ductal adenocarcinoma	Immunohistochemistry	Increased		Leung et al. 2012
Pancreatic intraepithelial neoplasia (PanIN)-2	Immunohistochemistry	Increased		Leung et al. 2012
PanIN-3	Immunohistochemistry	Increased		Leung et al. 2012
Pancreatic cancer	Immunohistochemistry	Increased		Xu et al. 2012
Pancreatic cancer	ELISA	Increased		Waraya et al. 2012

Chronic Pancreatitis

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
02551	3934	600181	HGNC:6526