Pancreatic Cancer Database

microRNA 221

Gene Symbol

MIR221

Chromosome Locus

Xp11.3

miRNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	qRT-PCR	Increased	8.8	du et al.
Invasive ductal adenocarcinoma	qRT-PCR	Increased	9	Park et al.
Invasive ductal denocarcinoma	RT-PCR	Increased	2	Zhang et al.
Intraductal papillary mucinous neoplasms	RT-PCR	Increased	6.6	Habbe et al.
Pancreatic cancer	qRT-PCR	Increased		Kawaguchi et al. 2013
Pancreatic cancer	qRT-PCR	Increased		Kawaguchi et al. 2013
Intraductal papillary mucinous neoplasms	qRT-PCR	Increased	2	Lubezky et al. 2013
Pancreatic cancer	miRNA microarray	Increased	3.7	Piepoli et al. 2012
Pancreatic ductal addenocarcinoma	qRT-PCR	Increased		Panarelli et al. 2012
Pancreatic cancer	miRNA microarray	Increased	3.8	Nakata et al. 2011
Pancreatic adenocarcinoma	RT-PCR	Increased		Papaconstantinou et al. 2012
Invasive ductal adenocarcinoma	miRNA microarray	Increased	0.5	Jamieson et al. 2011

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
HS766T	qRT-PCR	Increased	9	Park et al.
Panc-1	RT-PCR	Increased	2	Zhang et al.
MIA PaCa-2	RT-PCR	Increased	2	Zhang et al.
BxPC-3	RT-PCR	Increased	2	Zhang et al.
Hs766T	RT-PCR	Increased	2	Zhang et al.
ASPC-1	RT-PCR	Increased	2	Zhang et al.
Capan-1	RT-PCR	Increased	2	Zhang et al.
Capan-2	RT-PCR	Increased	2	Zhang et al.
Panc3.27	RT-PCR	Increased	2	Zhang et al.
HPAF-II	RT-PCR	Increased	2	Zhang et al.
PL45	RT-PCR	Increased	2	Zhang et al.

Expressed in Body Fluid

Secreted

-

Body Fluid

-

External Links

Entrez Gene	OMIM	HGNC	miRBase
407006	300568	31601	MI0000298

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."