Pancreatic Cancer Database

Galectin-3

Gene Symbol

LGALS3

Chromosome Locus

14q21-q22

Alternate Names

Lectin, galactose binding soluble 3; Macrophage galactose specific lectin; MAC2

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Intraductal papillary mucinous neoplasms	DNA microarray	Increased	4.8	Terris et al. 2002
Invasive ductal adenocarcinoma	In situ hybridization	Increased		Berberat et al. 2001
Invasive ductal adenocarcinoma	RT-PCR	Increased		Johnson et al. 2006
Invasive ductal adenocarcinoma	Northern blot	Increased	4.7	Berberat et al. 2001
Invasive ductal adenocarcinoma	DNA microarray	Increased	6.3	Johnson et al. 2006
Invasive ductal adenocarcinoma	DNA microarray	Increased	3.4	Lowe et al. 2007
Invasive ductal adenocarcinoma	DNA microarray	Increased	6.1	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	SAGE	Increased		Terris et al. 2002

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	Western blot	Increased		Chen et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Chen et al.
Intraductal papillary mucinous neoplasms	Immunohistochemistry	Increased		Terris et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Terris et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Berberat et al.
Invasive ductal adenocarcinoma	Western blot	Increased	2.5	Berberat et al.
Invasive ductal adenocarcinoma	Western blot	Increased		Shen et al.
Pancreatic ductal adenocarcinoma	Immunohistochemistry	Increased		Xie et al. 2012
Pancreatic ductal adenocarcinoma	ELISA	Increased		Xie et al. 2012
Pancreatic ductal adenocarcinoma	Time resolved fluorometric immunoassay (TRFIA)	Increased		Xie et al. 2012
Pancreatic ductal adenocarcinoma	Immunohistochemistry	Increased		Song et al. 2012

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
Protein	Western blot	Increased		Shen et al.

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
01090	3958	153619	HGNC:6563