Notch 3
Gene Symbol   NOTCH3 Chromosome Locus   19p13.2-p13.1
 
  Alternate Names    
     
 
Notch homolog 3; Neurogenic locus notch homolog protein 3
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma RT-PCR
Increased
2.9
Buchler et al. 2005
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
PANC-1 RT-PCR
Decreased
Mullendore et al.
Capan-1 RT-PCR
Decreased
Mullendore et al.
Colo 357 RT-PCR
Decreased
Mullendore et al.
CFPAC RT-PCR
Decreased
Mullendore et al.
MIA PaCa-2 RT-PCR
Decreased
Mullendore et al.
BxPC-3 RT-PCR
Decreased
Mullendore et al.
AsPC-1 RT-PCR
Decreased
Mullendore et al.
L3.6PL RT-PCR
Decreased
Mullendore et al.
PL-4 RT-PCR
Decreased
Mullendore et al.
PL-5 RT-PCR
Decreased
Mullendore et al.
PL-8 RT-PCR
Decreased
Mullendore et al.
PL-9 RT-PCR
Decreased
Mullendore et al.
PL-12 RT-PCR
Decreased
Mullendore et al.
PL-13 RT-PCR
Decreased
Mullendore et al.
XPA-1 RT-PCR
Decreased
Mullendore et al.
XPA-3 RT-PCR
Decreased
Mullendore et al.
XPA-4 RT-PCR
Decreased
Mullendore et al.
PANC-8.13 RT-PCR
Decreased
Mullendore et al.
PANC-3.27 RT-PCR
Decreased
Mullendore et al.
PANC-4.30 RT-PCR
Decreased
Mullendore et al.
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Buchler et al.
Pancreatic ductal adenocarcinoma Immunohistochemistry
Increased
Mann et al. 2012
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."