Pancreatic Cancer Database

Matrix metallopeptidase 2

Gene Symbol

MMP2

Chromosome Locus

16q13-q21

Alternate Names

Collagenase type 4, 72 kD; Collagenase type 4A; Gelatinase, 72 kD

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Increased	3.6	Lowe et al. 2007
Invasive ductal adenocarcinoma	Northern blot	Increased		Bramhall et al. 1997
Invasive ductal adenocarcinoma	In situ hybridization	Increased		Iacobuzio-Donahue et al. 2002
Invasive ductal adenocarcinoma	In situ hybridization	Increased		Bramhall et al. 1997
Invasive ductal adenocarcinoma	Northern blot	Increased		Ellenrieder et al. 1999

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Pancreatic cancer	Immunohistochemistry	Increased		Ohlund et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Schneiderhan et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Gurevich et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Bramhall et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Ellenrieder et al.
Invasive ductal adenocarcinoma	Other assays	Increased		Schneiderhan et al. 2007

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
00386	4313	120360	HGNC:7166