Pancreatic Cancer Database

Annexin A2

Gene Symbol

ANXA2

Chromosome Locus

15q21-q22

Alternate Names

PAP-IV; LPC2D; CAL1H

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Increased	2	Esposito et al. 2006

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Takano et al.
PanIN-2	DIGE	Increased	4.8	Sitek et al.
Invasive ductal adenocarcinoma	ICAT	Increased	2.7	Chen et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Tian et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Paciucci et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Paciucci et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Chen et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Ortiz-Zapater et al.
PanIN-2	Immunohistochemistry	Increased		Ortiz-Zapater et al.
PanIN-3	Immunohistochemistry	Increased		Ortiz-Zapater et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Chen et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Esposito et al.
PanIN-1A	Immunohistochemistry	Increased		Esposito et al.
PanIN-1B	Immunohistochemistry	Increased		Esposito et al.
PanIN-2	Immunohistochemistry	Increased		Esposito et al.
PanIN-3	Immunohistochemistry	Increased		Esposito et al.
Invasive ductal adenocarcinoma	Mass spectrometry	Increased		Tian et al.
Invasive ductal adenocarcinoma	Two dimensional electrophoresis	Increased		Tian et al.
Invasive ductal adenocarcinoma	Western blot	Increased	11.6	Crnogorac-Jurcevic et al.
Invasive ductal adenocarcinoma	Western blot	Increased		Tian et al.
Invasive ductal adenocarcinoma	Western blot	Increased		Chen et al.
Invasive ductal adenocarcinoma	Western blot	Increased	2.7	Chen et al.
Invasive ductal adenocarcinoma	Label free quantitation, Mass spectrometry	Increased	3.3	Pan et al. 2011

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
SK-PC-1	Western blot	Increased		Paciucci et al. 1998
AsPC-1	Western blot	Increased		Paciucci et al. 1998
BxPC3	Western blot	Increased		Ortiz-Zapater et al. 2007
HPDE	Western blot	Increased		Ortiz-Zapater et al. 2007
SK-PC-1	Western blot	Increased		Ortiz-Zapater et al. 2007
PANC-1	Western blot	Increased		Ortiz-Zapater et al. 2007
Hs766T	Western blot	Increased		Ortiz-Zapater et al. 2007

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
Protein	Label free quantitation, Mass spectrometry	Increased	3.1	Pan et al. 2011

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
01061	302	151740	HGNC:537

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."