Pancreatic Cancer Database

Connexin 26

Gene Symbol

GJB2

Chromosome Locus

13q11-q12

Alternate Names

Gap junction protein, 26 KD; Gap junction protein, beta 2; CX26

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Increased	7.3	Iacobuzio-Donahue et al. 2002
Invasive ductal adenocarcinoma	DNA microarray	Increased	3	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	RT-PCR	Increased		Pfeffer et al. 2004
Invasive ductal adenocarcinoma	DNA microarray	Increased	5.4	Lowe et al. 2007
Invasive ductal adenocarcinoma	DNA microarray	Increased	10.8	Pfeffer et al. 2004

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Pancreatic cancer	Immunohistochemistry	Increased		Kyo et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Pfeffer et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
RNA	RT-PCR	Increased	2.9	Pfeffer et al.

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
00413	2706	121011	HGNC:4284