Pancreatic Cancer Database

S100 calcium binding protein A6

Gene Symbol

S100A6

Chromosome Locus

1q21

Alternate Names

S100 Calcium binding protein A6; PRA; MLN 4

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA Microarray	Increased		Olakowski et al.
Intraductal papillary mucinous neoplasms	DNA microarray	Increased	16.8	Sato et al. 2004
Intraductal papillary mucinous neoplasms	RT-PCR	Increased		Ohuchida et al. 2007
Invasive ductal adenocarcinoma	RT-PCR	Increased		Ohuchida et al. 2007
Invasive ductal adenocarcinoma	DNA microarray	Increased	44	Logsdon et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	2.7	Buchholz et al. 2005
Invasive ductal adenocarcinoma	RT-PCR	Increased		Ohuchida et al. 2005
Invasive ductal adenocarcinoma	DNA microarray	Increased	7	Crnogorac-Jurcevic et al. 2003
PanIN-1A	DNA microarray	Increased	1.8	Prasad et al. 2005
PanIN-1B	DNA microarray	Increased	1.8	Prasad et al. 2005
PanIN-2	DNA microarray	Increased	1.8	Prasad et al. 2005

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Logsdon et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Crnogorac-Jurcevic et al.
PanIN-3	Immunohistochemistry	Increased		Ohuchida et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Ohuchida et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Shekouh et al.
Invasive ductal adenocarcinoma	Mass spectrometry	Increased		Shekouh et al.
Invasive ductal adenocarcinoma	Two dimensional electrophoresis	Increased		Shekouh et al.
Invasive ductal adenocarcinoma	Label free quantitation, Mass spectrometry	Increased	8.3	Pan et al. 2011

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
Protein	Label free quantitation, Mass spectrometry	Increased	3.3	Pan et al. 2011
Protein	Label free quantitation, Mass spectrometry	Increased	5.6	Pan et al. 2011

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
00237	6277	114110	HGNC:10496