Chemokine (C-X-C motif) receptor 4
Gene Symbol   CXCR4 Chromosome Locus   2q21
 
  Alternate Names    
     
 
Chemokine receptor 4; Seven transmembrane helix receptor; Chemokine (C-X-C motif) receptor 4 isoform b
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Endocrine Neoplasms DNA microarray
Increased
5.3
Maitra et al.
Invasive ductal adenocarcinoma RT-PCR
Increased
Johnson et al. 2006
Invasive ductal adenocarcinoma DNA microarray
Increased
13.3
Johnson et al. 2006
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
BxPC-3 RT-PCR
Increased
Matsuo et al.
AsPC-1 RT-PCR
Increased
Matsuo et al.
MIA PaCa-2 RT-PCR
Increased
Matsuo et al.
Panc-1 RT-PCR
Increased
Matsuo et al.
Capan-2 RT-PCR
Increased
Matsuo et al.
SW 1990 RT-PCR
Increased
Matsuo et al.
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Wang et al.
Pancreatic ductal adenocarcinoma Immunohistochemistry
Increased
Bachet et al. 2012
pancreatic adenocarcinoma Immunohistochemistry
Increased
Gebauer et al. 2011
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
RNA DNA microarray
Increased
2
 Binkley et al. 2004
RNA DNA microarray
Increased
5.2
 Rogers et al. 2006
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."