Serpin peptidase inhibitor, clade B (ovalbumin), member 5
Gene Symbol   SERPINB5 Chromosome Locus   18q21.3
 
  Alternate Names    
     
 
Protease inhibitor 5; PI5; Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Intraductal papillary mucinous neoplasms DNA microarray
Increased
46
Sato et al. 2004
Invasive ductal adenocarcinoma DNA microarray
Increased
23.1
Pfeffer et al. 2004
Invasive ductal adenocarcinoma DNA microarray
Increased
24
Logsdon et al. 2003
Invasive ductal adenocarcinoma DNA microarray
Increased
4
Crnogorac-Jurcevic et al. 2003
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
BxPC-3 Northern blot
Increased
Maass et al. 2001
AsPC-1 Northern blot
Increased
Maass et al. 2001
BxPC-3 DNA microarray
Increased
25
Logsdon et al. 2003
MIA PaCa-2 DNA microarray
Increased
25
Logsdon et al. 2003
CFPAC-1 DNA microarray
Increased
25
Logsdon et al. 2003
HPAC DNA microarray
Increased
25
Logsdon et al. 2003
MPanc-96 DNA microarray
Increased
25
Logsdon et al. 2003
SU.86.86 DNA microarray
Increased
25
Logsdon et al. 2003
SW1990 DNA microarray
Increased
25
Logsdon et al. 2003
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma SILAC, Tandem mass spectrometry
Increased
2.4
Yu et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Ohike et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Lim et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Maass et al.
PanIN-3 Immunohistochemistry
Increased
Maass et al.
PanIN-1A Immunohistochemistry
Increased
Cao et al.
PanIN-1B Immunohistochemistry
Increased
Cao et al.
PanIN-2 Immunohistochemistry
Increased
Cao et al.
PanIN-3 Immunohistochemistry
Increased
Cao et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Cao et al.
Intraductal papillary mucinous neoplasm with low-grade dysplasia Immunohistochemistry
Increased
Kashima et al.
Intraductal papillary mucinous neoplasm with moderate dysplasia Immunohistochemistry
Increased
Kashima et al.
Intraductal papillary mucinous neoplasm with high-grade dysplasia (ca Immunohistochemistry
Increased
Kashima et al.
Mucinous cystic neoplasm with moderate dysplasia Immunohistochemistry
Increased
Oh et al.
Mucinous cystic neoplasm with an associated invasive carcinoma Immunohistochemistry
Increased
Oh et al.
Intraductal papillary mucinous neoplasm with moderate dysplasia Immunohistochemistry
Increased
Oh et al.
Intraductal papillary Immunohistochemistry
Increased
Oh et al.
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
BxPC-3 Immunohistochemistry
Increased
Maass et al. 2001
AsPC-1 Immunohistochemistry
Increased
Maass et al. 2001
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted
Body Fluid
Serum Yu et al.
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."