Pancreatic Cancer Database

Serpin peptidase inhibitor, clade B (ovalbumin), member 5

Gene Symbol

SERPINB5

Chromosome Locus

18q21.3

Alternate Names

Protease inhibitor 5; PI5; Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Intraductal papillary mucinous neoplasms	DNA microarray	Increased	46	Sato et al. 2004
Invasive ductal adenocarcinoma	DNA microarray	Increased	23.1	Pfeffer et al. 2004
Invasive ductal adenocarcinoma	DNA microarray	Increased	24	Logsdon et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	4	Crnogorac-Jurcevic et al. 2003

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	SILAC, Tandem mass spectrometry	Increased	2.4	Yu et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Ohike et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Lim et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Maass et al.
PanIN-3	Immunohistochemistry	Increased		Maass et al.
PanIN-1A	Immunohistochemistry	Increased		Cao et al.
PanIN-1B	Immunohistochemistry	Increased		Cao et al.
PanIN-2	Immunohistochemistry	Increased		Cao et al.
PanIN-3	Immunohistochemistry	Increased		Cao et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Cao et al.
Intraductal papillary mucinous neoplasm with low-grade dysplasia	Immunohistochemistry	Increased		Kashima et al.
Intraductal papillary mucinous neoplasm with moderate dysplasia	Immunohistochemistry	Increased		Kashima et al.
Intraductal papillary mucinous neoplasm with high-grade dysplasia (ca	Immunohistochemistry	Increased		Kashima et al.
Mucinous cystic neoplasm with moderate dysplasia	Immunohistochemistry	Increased		Oh et al.
Mucinous cystic neoplasm with an associated invasive carcinoma	Immunohistochemistry	Increased		Oh et al.
Intraductal papillary mucinous neoplasm with moderate dysplasia	Immunohistochemistry	Increased		Oh et al.
Intraductal papillary	Immunohistochemistry	Increased		Oh et al.

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

Serum

External Links

HPRD	Entrez Gene	OMIM	HGNC
01111	5268	154790	HGNC:8949