Pancreatic Cancer Database

Enolase 1, (alpha)

Gene Symbol

ENO1

Chromosome Locus

1p36.3-p36.2

Alternate Names

Enolase, alpha; Phosphopyruvate hydratase; PPH

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Increased		Cappello et al.
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma	DNA microarray	Increased	3.2	Sato et al. 2004
Intraductal papillary mucinous neoplasms	DNA microarray	Increased	10	Sato et al. 2004
Invasive ductal adenocarcinoma	DNA microarray	Increased	5.1	Iacobuzio-Donahue et al. 2003
PanIN-1A	DNA microarray	Increased	2.1	Prasad et al. 2005
PanIN-1B	DNA microarray	Increased	2.1	Prasad et al. 2005
PanIN-2	DNA microarray	Increased	2.1	Prasad et al. 2005

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	SILAC, Tandem mass spectrometry	Increased	2.5	Yu et al.
Invasive ductal adenocarcinoma	Western blot	Increased		Cappello et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Cappello et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Shen et al.
Invasive ductal adenocarcinoma	Mass spectrometry	Increased	4.6	Shen et al.
Invasive ductal adenocarcinoma	Two dimensional electrophoresis	Increased	4.6	Shen et al.
Invasive ductal adenocarcinoma	Western blot	Increased	4.6	Shen et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
PANC-1	SILAC, Tandem mass spectrometry	Decreased		Gronborg et al.
Aspc-1	Western blot	Increased		Shen et al. 2004
Capan-1	Western blot	Increased		Shen et al. 2004
Capan-2	Western blot	Increased		Shen et al. 2004
Hs766T	Western blot	Increased		Shen et al. 2004
MiaPaCa-2	Western blot	Increased		Shen et al. 2004
Panc-1	Western blot	Increased		Shen et al. 2004
Panc-3	Western blot	Increased		Shen et al. 2004
Panc-48	Western blot	Increased		Shen et al. 2004
Panc-28	Western blot	Increased		Shen et al. 2004
Su-8666	Western blot	Increased		Shen et al. 2004
HPAF-11	Western blot	Increased		Shen et al. 2004
BxPC3	Western blot	Increased		Shen et al. 2004
	Western blot	Increased		Shen et al. 2004

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

Serum

External Links

HPRD	Entrez Gene	OMIM	HGNC
01400	2023	172430	HGNC:3350