microRNA 21
Gene Symbol   MIR21 Chromosome Locus   17q23.1
 
  miRNA Alterations    
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
PanIN-3 qRT-PCR
Increased
2.5
Ryu et al.
Invasive ductal adenocarcinoma qRT-PCR
Increased
20.6
du et al.
Invasive ductal adenocarcinoma qRT-PCR
Increased
2
Park et al.
Invasive ductal adenocarcinoma qRT-PCR
Increased
2.4
Park et al.
Invasive ductal adenocarcinoma RT-PCR
Increased
Bhatti et al.
Intraductal papillary mucinous neoplasms RT-PCR
Increased
12.1
Habbe et al.
Pancreatic cancer In situ hybridization
Increased
Dillhoff et al.
Pancreatic ductal adenocarcinoma RT-PCR
Increased
2.3
Kong et al.
Invasive ductal adenocarcinoma RT-PCR
Increased
Moriyama et al.
Invasive ductal adenocarcinoma RT-PCR
Increased
Zhu et al.
Pancreatic cancer miRNA microarray
Increased
2.7
Piepoli et al. 2012
Pancreatic ductal addenocarcinoma qRT-PCR
Increased
Panarelli et al. 2012
Pancreatic adenocarcinoma RT-PCR
Increased
5.6
Papaconstantinou et al. 2012
Pancreatic adenocarcinoma miRNA microarray
Increased
4.4
Schultz et al. 2012
Pancreatic intraepithelial neoplasia TaqMan Array Human microRNA cards
Increased
15.2
Yu et al. 2011
Invasive ductal adenocarcinoma RT-qPCR
Increased
Jiao et al. 2012
Serous microcystic adenoma RT-qPCR
Increased
Jiao et al. 2012
pancreatic ductal adenocarcinoma miRNA microarray
Increased
3.6
Nagao et al. 2011
pancreatic ductal adenocarcinoma RT-PCR
Increased
Nagao et al. 2011
Pancreatic cancer miRNA microarray
Increased
2.9
Nakata et al. 2011
Invasive ductal adenocarcinoma miRNA microarray
Increased
0.3
Jamieson et al. 2011
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
HS766T qRT-PCR
Increased
2
Park et al.
MIA-Pa-Ca-2 RT-PCR
Increased
Bhatti et al.
HUP-T3 RT-PCR
Increased
Bhatti et al.
PSN-1 RT-PCR
Increased
Bhatti et al.
AsPC-1 RT-PCR
Increased
1.1
Moriyama et al.
KP-1N RT-PCR
Increased
1.1
Moriyama et al.
KP-2 RT-PCR
Increased
1.1
Moriyama et al.
KP-3 RT-PCR
Increased
1.1
Moriyama et al.
PANC-1 RT-PCR
Increased
1.1
Moriyama et al.
SUIT-2 RT-PCR
Increased
1.1
Moriyama et al.
CAPAN-1 RT-PCR
Increased
1.1
Moriyama et al.
CAPAN-2 RT-PCR
Increased
1.1
Moriyama et al.
CFPAC-1 RT-PCR
Increased
1.1
Moriyama et al.
H48N RT-PCR
Increased
1.1
Moriyama et al.
HS766T RT-PCR
Increased
1.1
Moriyama et al.
SW1990 RT-PCR
Increased
1.1
Moriyama et al.
CFPAC-1 RT-PCR
Increased
Zhu et al.
PANC-1 RT-PCR
Increased
Zhu et al.
RT-PCR
Increased
Zhu et al.
 
   
 
  Expressed in Body Fluid  
     
 
     
 
Secreted
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
Entrez Gene
OMIM
HGNC
miRBase
MI0000077
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."