Pancreatic Cancer Database

Jagged 2

Gene Symbol

JAG2

Chromosome Locus

14q32

Alternate Names

HJ2; Jagged 2 isoform b precursor; Jagged 2 isoform a precursor

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	RT-PCR	Increased	6.7	Buchler et al. 2005

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
PANC-1	RT-PCR	Increased		Mullendore et al.
CAPAN-1	RT-PCR	Increased		Mullendore et al.
MIAPaCa-2	RT-PCR	Increased		Mullendore et al.
BxPC-3	RT-PCR	Increased		Mullendore et al.
AsPc-1	RT-PCR	Increased		Mullendore et al.
L3.6PL	RT-PCR	Increased		Mullendore et al.
PL-4	RT-PCR	Increased		Mullendore et al.
PL-5	RT-PCR	Increased		Mullendore et al.
PL-8	RT-PCR	Increased		Mullendore et al.
PL-9	RT-PCR	Increased		Mullendore et al.
	RT-PCR	Increased		Mullendore et al.
PL-13	RT-PCR	Increased		Mullendore et al.
XPA-1	RT-PCR	Increased		Mullendore et al.
XPA-3	RT-PCR	Increased		Mullendore et al.
XPA-4	RT-PCR	Increased		Mullendore et al.
Panc-8.13	RT-PCR	Increased		Mullendore et al.
Panc-4.30	RT-PCR	Increased		Mullendore et al.
MIA PaCa-2	RT-PCR	Increased		Buchler et al. 2005
T3M4	RT-PCR	Increased		Buchler et al. 2005

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

-

Secreted

-

Body Fluid

-

External Links

HPRD	Entrez Gene	OMIM	HGNC
03981	3714	602570	HGNC:6189

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."