Tumor protein p53
Gene Symbol   TP53 Chromosome Locus   17p13.1
 
  Alternate Names    
     
 
Transformation related protein 53; TRP53
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Endocrine Neoplasms Northern blot
Increased
Bartz et al. 1996
Invasive ductal adenocarcinoma DNA microarray
Increased
2.3
Buchholz et al. 2005
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
Huh7 Northern blot
Increased
Bartz et al. 1996
PLC Northern blot
Increased
Bartz et al. 1996
Capan1 Northern blot
Increased
Bartz et al. 1996
Panc-1 Northern blot
Increased
Bartz et al. 1996
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Adenosquamous carcinoma Immunohistochemistry
Increased
Brody et al.
PanIN-3 Immunohistochemistry
Increased
Koorstra et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Koorstra et al.
Invasive ductal adenocarcinoma ELISA
Increased
Suwa et al.
Invasive ductal adenocarcinoma ELISA
Increased
Gansauge et al.
Invasive ductal adenocarcinoma ELISA
Increased
Attallah et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Pavelic et al.
Mucinous cystic neoplasms Immunohistochemistry
Increased
Pavelic et al.
Intraductal papillary mucinous neoplasm with high-grade dysplasia (carcinoma in situ) Immunohistochemistry
Increased
Miyasaka et al.
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma Immunohistochemistry
Increased
Miyasaka et al.
Intraductal papillary mucinous neoplasms Immunohistochemistry
Increased
Usui et al.
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma Immunohistochemistry
Increased
Usui et al.
Intraductal papillary mucinous neoplasms Immunohistochemistry
Increased
Biankin et al.
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma Immunohistochemistry
Increased
Biankin et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Biankin et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Tomaszewska et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Suwa et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Gansauge et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Dang et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Suzuki et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Zhao et al.
Mucinous cystic neoplasms Immunohistochemistry
Increased
Zhao et al.
PanIN-2 Immunohistochemistry
Increased
Luttges et al.
PanIN-3 Immunohistochemistry
Increased
Luttges et al.
PanIN-2 Immunohistochemistry
Increased
Luttges et al.
PanIN-3 Immunohistochemistry
Increased
Luttges et al.
PanIN-2 Immunohistochemistry
Increased
Biankin et al.
PanIN-3 Immunohistochemistry
Increased
Biankin et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Biankin et al.
PanIN-3 Immunohistochemistry
Increased
Maitra et al.
PanIN-3 Immunohistochemistry
Increased
Moriya et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Moriya et al.
Intraductal papillary mucinous neoplasm with low-grade dysplasia Immunohistochemistry
Increased
Abe et al.
Intraductal papillary mucinous neoplasm with moderate dysplasia Immunohistochemistry
Increased
Abe et al.
Intraductal papillary mucinous neoplasm with high-grade dysplasia (ca Immunohistochemistry
Increased
Abe et al.
Endocrine Neoplasms Western blot
Increased
Bartz et al.
Invasive ductal adenocarcinoma Western blot
Increased
Attallah et al.
Invasive ductal adenocarcinoma Western blot
Increased
Gansauge et al.
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."