Pancreatic Cancer Database

Synuclein, gamma (breast cancer-specific protein 1)

Gene Symbol

SNCG

Chromosome Locus

10q23.2-q23.3

Alternate Names

SR; BCSG1; PERSYN

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Endocrine Neoplasms	DNA microarray	Increased	3	Kayton et al. 2003
Invasive ductal adenocarcinoma	SAGE	Increased		Hustinx et al. 2004
Invasive ductal adenocarcinoma	DNA microarray	Increased	3.4	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	Northern blot	Increased		Li et al. 2004
Invasive ductal adenocarcinoma	RT-PCR	Increased		Li et al. 2004

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
AsPc1	DNA microarray	Increased	7.4	Iacobuzio-Donahue et al. 2003
BxPc3	DNA microarray	Increased	7.4	Iacobuzio-Donahue et al. 2003
CAPAN1	DNA microarray	Increased	7.4	Iacobuzio-Donahue et al. 2003
CAPAN2	DNA microarray	Increased	7.4	Iacobuzio-Donahue et al. 2003
CFPAC1	DNA microarray	Increased	7.4	Iacobuzio-Donahue et al. 2003
Hs766T	DNA microarray	Increased	7.4	Iacobuzio-Donahue et al. 2003
MiaPaca2	DNA microarray	Increased	7.4	Iacobuzio-Donahue et al. 2003
Panc-1	DNA microarray	Increased	7.4	Iacobuzio-Donahue et al. 2003
Su86.86	DNA microarray	Increased	7.4	Iacobuzio-Donahue et al. 2003
AsPc-1	RT-PCR	Increased		Li et al. 2004
MDAPanc28	RT-PCR	Increased		Li et al. 2004
Capan-1	RT-PCR	Increased		Li et al. 2004
Capan-2	RT-PCR	Increased		Li et al. 2004
HS766T	RT-PCR	Increased		Li et al. 2004
MDAPanc3	RT-PCR	Increased		Li et al. 2004
Colo357FG	RT-PCR	Increased		Li et al. 2004
BxPc3	RT-PCR	Increased		Li et al. 2004
MDAPanc28	Northern blot	Increased		Li et al. 2004
BxPc3	Northern blot	Increased		Li et al. 2004
Capan-1	Northern blot	Increased		Li et al. 2004
Capan-2	Northern blot	Increased		Li et al. 2004
HS766T	Northern blot	Increased		Li et al. 2004
MDAPanc3	Northern blot	Increased		Li et al. 2004
Colo357FG	Northern blot	Increased		Li et al. 2004
AsPc-1	Northern blot	Increased		Li et al. 2004
AsPC1	SAGE	Increased		Hustinx et al. 2004
PL11	SAGE	Increased		Hustinx et al. 2004
MiaPaCa2	SAGE	Increased		Hustinx et al. 2004
BXPC3	SAGE	Increased		Hustinx et al. 2004
CFPAC1	SAGE	Increased		Hustinx et al. 2004
PL13	SAGE	Increased		Hustinx et al. 2004
PL3	SAGE	Increased		Hustinx et al. 2004
CAPAN2	SAGE	Increased		Hustinx et al. 2004
PL6	SAGE	Increased		Hustinx et al. 2004
PL4	SAGE	Increased		Hustinx et al. 2004
Hs766T	SAGE	Increased		Hustinx et al. 2004
Panc1	SAGE	Increased		Hustinx et al. 2004
PL12	SAGE	Increased		Hustinx et al. 2004
Su8717	SAGE	Increased		Hustinx et al. 2004

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Hibi et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Li et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Iacobuzio-Donahue et al.
Invasive ductal adenocarcinoma	Western blot	Increased		Li et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
MDAPanc-28	Western blot	Increased		Li et al. 2004
BxPC-3	Western blot	Increased		Li et al. 2004
Capan-1	Western blot	Increased		Li et al. 2004
Capan-2	Western blot	Increased		Li et al. 2004
HS766T	Western blot	Increased		Li et al. 2004
MDAPanc3	Western blot	Increased		Li et al. 2004
Colo357F	Western blot	Increased		Li et al. 2004

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
04297	6623	602998	HGNC:11141

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."