Interleukin 18
Gene Symbol   IL18 Chromosome Locus   11q22.2-q22.3
 
  Alternate Names    
     
 
Interferon gamma inducing factor; IFN gamma inducing factor; Interleukin 1 gamma
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma SAGE
Increased
Ryu et al. 2002
Invasive ductal adenocarcinoma RT-PCR
Increased
Bellone et al. 2005
Invasive ductal adenocarcinoma RT-PCR
Increased
Carbone et al. 2005
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
Capan-2 RT-PCR
Increased
Carbone et al. 2005
PT-45 RT-PCR
Increased
Carbone et al. 2005
Capan-2 RT-PCR
Increased
Bellone et al. 2005
AsPc1 SAGE
Increased
Ryu et al. 2002
CAPAN1 SAGE
Increased
Ryu et al. 2002
CAPAN2 SAGE
Increased
Ryu et al. 2002
Panc-1 SAGE
Increased
Ryu et al. 2002
PL45 SAGE
Increased
Ryu et al. 2002
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Pancreatic ductal adenocarcinoma ELISA
Increased
Carbone et al.
Invasive ductal adenocarcinoma ELISA
Increased
Bellone et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Bellone et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Carbone et al.
Pancreatic ductal adenocarcinoma Antibody microarray
Increased
Kelber et al. 2012
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
PT-45 ELISA
Increased
Bellone et al. 2005
Capan-2 ELISA
Increased
Bellone et al. 2005
BxPC-3 ELISA
Increased
Bellone et al. 2005
PANC-1 ELISA
Increased
Bellone et al. 2005
MIAPaCa-2 ELISA
Increased
Bellone et al. 2005
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted
Body Fluid
Serum Carbone et al.
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."