Pancreatic Cancer Database

Anterior gradient homolog 2 (Xenopus laevis)

Gene Symbol

AGR2

Chromosome Locus

7p21.3

Alternate Names

Secreted cement gland protein XAG2 homolog; XAG2 homolog long protein; Hypothetical protein AGR2

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	RT-PCR	Increased	14	Ramachandran et al.
Invasive ductal adenocarcinoma	DNA microarray	Increased	6.7	Lowe et al. 2007
Invasive ductal adenocarcinoma	DNA microarray	Increased	2.3	Kristiansen et al. 2006
Invasive ductal adenocarcinoma	DNA microarray	Increased	4	Crnogorac-Jurcevic et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	5	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	2.8	Buchholz et al. 2005
Invasive ductal adenocarcinoma	SAGE	Increased		Ryu et al. 2002
PanIN-1A	DNA microarray	Increased	2.3	Buchholz et al. 2005
PanIN-1B	DNA microarray	Increased	2.3	Buchholz et al. 2005
PanIN-1A	DNA microarray	Increased	2.1	Prasad et al. 2005
PanIN-1B	DNA microarray	Increased	2.1	Prasad et al. 2005
PanIN-2	DNA microarray	Increased	2.1	Prasad et al. 2005
PanIN-2	DNA microarray	Increased	2.6	Buchholz et al. 2005

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Ramachandran et al.
PanIN-1, PanIN-2, and PanIN-3	Immunohistochemistry	Increased		Ramachandran et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Missiaglia et al.
pancreatic ductal adenocarcinoma	Label free quantitation, Mass spectrometry	Increased	4	Pan et al. 2011

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
Protein	Label free quantitation, Mass spectrometry	Increased	3.9	Pan et al. 2011

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
05896	10551	606358	HGNC:328