Pancreatic Cancer Database

Insulin-like growth factor 2 mRNA binding protein 3

Gene Symbol

IGF2BP3

Chromosome Locus

7p11

Alternate Names

IMP3; KOC1; VICKZ3

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Increased	3	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	5.9	Iacobuzio-Donahue et al. 2002
Invasive ductal adenocarcinoma	DNA microarray	Increased	7.4	Grutzmann et al. 2004
Invasive ductal adenocarcinoma	Northern blot	Increased		Mueller-Pillasch et al. 1997

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
AsPc1	DNA microarray	Increased	5.9	Iacobuzio-Donahue et al. 2002
BxPc3	DNA microarray	Increased	5.9	Iacobuzio-Donahue et al. 2002
CAPAN1	DNA microarray	Increased	5.9	Iacobuzio-Donahue et al. 2002
CAPAN2	DNA microarray	Increased	5.9	Iacobuzio-Donahue et al. 2002
CFPAC1	DNA microarray	Increased	5.9	Iacobuzio-Donahue et al. 2002
COLO357	DNA microarray	Increased	5.9	Iacobuzio-Donahue et al. 2002
Hs766T	DNA microarray	Increased	5.9	Iacobuzio-Donahue et al. 2002
MiaPaCa2	DNA microarray	Increased	5.9	Iacobuzio-Donahue et al. 2002
Panc-1	DNA microarray	Increased	5.9	Iacobuzio-Donahue et al. 2002
Su86.86	DNA microarray	Increased	5.9	Iacobuzio-Donahue et al. 2002
Patu 8988s	Northern blot	Increased		Mueller-Pillasch et al. 1997
Patu 8988t	Northern blot	Increased		Mueller-Pillasch et al. 1997
Panc 1	Northern blot	Increased		Mueller-Pillasch et al. 1997
HPAF	Northern blot	Increased		Mueller-Pillasch et al. 1997
MiaPaca 2	Northern blot	Increased		Mueller-Pillasch et al. 1997
Patu II	Northern blot	Increased		Mueller-Pillasch et al. 1997
Dan-G	Northern blot	Increased		Mueller-Pillasch et al. 1997
Patu 8902	Northern blot	Increased		Mueller-Pillasch et al. 1997
Capan II	Northern blot	Increased		Mueller-Pillasch et al. 1997
Capan I	Northern blot	Increased		Mueller-Pillasch et al. 1997
PC2	Northern blot	Increased		Mueller-Pillasch et al. 1997
ASPC1	Northern blot	Increased		Mueller-Pillasch et al. 1997
SKPC1	Northern blot	Increased		Mueller-Pillasch et al. 1997
IMIM-PC-1	Northern blot	Increased		Mueller-Pillasch et al. 1997
IMIM-PC-2	Northern blot	Increased		Mueller-Pillasch et al. 1997

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Pancreatic ductal adenocarcinoma	Immunohistochemistry	Increased		Schaeffer et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Zhao et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
16306	10643	608259	HGNC:28868

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."