Serine peptidase inhibitor, Kunitz type, 2
Gene Symbol   SPINT2 Chromosome Locus   19q13.1
 
  Alternate Names    
     
 
Kunitz type protease inhibitor 2; Placental bikunin; Hepatocyte growth fator activator inhibitor 2
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma DNA microarray
Increased
4
Campagna et al.
Invasive ductal adenocarcinoma SAGE
Increased
Hustinx et al. 2004
Invasive ductal adenocarcinoma Northern blot
Increased
Muller-Pillasch et al. 1998
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
AsPC1 SAGE
Increased
Hustinx et al. 2004
PL11 SAGE
Increased
Hustinx et al. 2004
MiaPaCa2 SAGE
Increased
Hustinx et al. 2004
BXPC3 SAGE
Increased
Hustinx et al. 2004
CFPAC1 SAGE
Increased
Hustinx et al. 2004
PL13 SAGE
Increased
Hustinx et al. 2004
PL3 SAGE
Increased
Hustinx et al. 2004
CAPAN2 SAGE
Increased
Hustinx et al. 2004
PL6 SAGE
Increased
Hustinx et al. 2004
PL4 SAGE
Increased
Hustinx et al. 2004
Hs766T SAGE
Increased
Hustinx et al. 2004
Panc1 SAGE
Increased
Hustinx et al. 2004
PL12 SAGE
Increased
Hustinx et al. 2004
Su8719 SAGE
Increased
Hustinx et al. 2004
Patu8988s Northern blot
Increased
Muller-Pillasch et al. 1998
Patu8988t Northern blot
Increased
Muller-Pillasch et al. 1998
Panc1 Northern blot
Increased
Muller-Pillasch et al. 1998
HPAF Northern blot
Increased
Muller-Pillasch et al. 1998
Patu II Northern blot
Increased
Muller-Pillasch et al. 1998
Dan-G Northern blot
Increased
Muller-Pillasch et al. 1998
Patu8902 Northern blot
Increased
Muller-Pillasch et al. 1998
Capan II Northern blot
Increased
Muller-Pillasch et al. 1998
Capan I Northern blot
Increased
Muller-Pillasch et al. 1998
PC2 Northern blot
Increased
Muller-Pillasch et al. 1998
ASPC1 Northern blot
Increased
Muller-Pillasch et al. 1998
SKPC1 Northern blot
Increased
Muller-Pillasch et al. 1998
IMIM PC2 Northern blot
Increased
Muller-Pillasch et al. 1998
IMIM PC1 Northern blot
Increased
Muller-Pillasch et al. 1998
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma ICAT
Increased
2.8
Chen et al.
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."