Pancreatic Cancer Database

Mucin 4

Gene Symbol

MUC4

Chromosome Locus

3q29

Alternate Names

Mucin 4 isoform d; Mucin 4 isoform e; HSA276359

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	RT-PCR	Increased		Andrianifahanana et al. 2001
Invasive ductal adenocarcinoma	RT-PCR	Increased		Li et al. 2005
Invasive ductal adenocarcinoma	DNA microarray	Increased	24.6	Segara et al. 2005
Invasive ductal adenocarcinoma	DNA microarray	Increased	3	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	RT-PCR	Increased		Andrianifahanana et al. 2006
PanIN-1A	In situ hybridization	Increased		Park et al. 2003
PanIN-1B	In situ hybridization	Increased		Park et al. 2003
PanIN-2	In situ hybridization	Increased		Park et al. 2003
PanIN-3	In situ hybridization	Increased		Park et al. 2003
Invasive ductal adenocarcinoma	In situ hybridization	Increased		Park et al. 2003

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
SC2P9	RT-PCR	Increased		Andrianifahanana et al. 2001
Capan 1	RT-PCR	Increased		Andrianifahanana et al. 2001
Capan 2	RT-PCR	Increased		Andrianifahanana et al. 2001
HPAF	RT-PCR	Increased		Andrianifahanana et al. 2001
ASPC-1	RT-PCR	Increased		Andrianifahanana et al. 2001
T3M4	RT-PCR	Increased		Andrianifahanana et al. 2001
Colo357	RT-PCR	Increased		Andrianifahanana et al. 2001
BxPC3	RT-PCR	Increased		Andrianifahanana et al. 2001
HPAC	RT-PCR	Increased		Andrianifahanana et al. 2001
QGP1	RT-PCR	Increased		Andrianifahanana et al. 2001
Panc89	RT-PCR	Increased		Andrianifahanana et al. 2001
Suit2	RT-PCR	Increased		Singh et al. 2006
S2CP9	RT-PCR	Increased		Singh et al. 2006
Colo357	RT-PCR	Increased		Singh et al. 2006
SW1990	RT-PCR	Increased		Singh et al. 2006
AsPc1	RT-PCR	Increased		Singh et al. 2006
BxPc3	RT-PCR	Increased		Singh et al. 2006
QGP1	RT-PCR	Increased		Singh et al. 2006
CaPan1	RT-PCR	Increased		Singh et al. 2006
CaPan2	RT-PCR	Increased		Singh et al. 2006
HPAF	RT-PCR	Increased		Singh et al. 2006
HPAC	RT-PCR	Increased		Singh et al. 2006
T3M4	RT-PCR	Increased		Singh et al. 2006
CFPAC1	RT-PCR	Increased		Singh et al. 2006
BxPC3	RT-PCR	Increased		Andrianifahanana et al. 2006
CaPan-1	RT-PCR	Increased		Andrianifahanana et al. 2006
Colo357	RT-PCR	Increased		Andrianifahanana et al. 2006
ASPC-1	RT-PCR	Increased		Andrianifahanana et al. 2006
HPAC	RT-PCR	Increased		Andrianifahanana et al. 2006
HPAF	RT-PCR	Increased		Andrianifahanana et al. 2006
T3M4	RT-PCR	Increased		Andrianifahanana et al. 2006
QGP1	RT-PCR	Increased		Andrianifahanana et al. 2006

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Pancreatic ductal adenocarcinoma	Immunohistochemistry	Increased		Fauquette et al.
Intraductal papillary mucinous neoplasms	Immunohistochemistry	Increased		Kanno et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Saitou et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Andrianifahanana et al.
PanIN-1A	Immunohistochemistry	Increased		Swartz et al.
PanIN-1B	Immunohistochemistry	Increased		Swartz et al.
PanIN-2	Immunohistochemistry	Increased		Swartz et al.
PanIN-3	Immunohistochemistry	Increased		Swartz et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Swartz et al.
PanIN-1A	Immunohistochemistry	Increased		Park et al.
PanIN-1B	Immunohistochemistry	Increased		Park et al.
PanIN-2	Immunohistochemistry	Increased		Park et al.
PanIN-3	Immunohistochemistry	Increased		Park et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Park et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
11829	4585	158372	HGNC:7514

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."