Epidermal growth factor receptor
Gene Symbol   EGFR Chromosome Locus   7p12
 
  Alternate Names    
     
 
Epidermal growth factor receptor isoform d; Epidermal growth factor receptor isoform b; Epidermal growth factor receptor isoform c
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma Northern blot
Increased
3
Streit et al.
Pancreatic ductal adenocarcinoma RT-PCR
Increased
2.3
Xue et al.
Invasive ductal adenocarcinoma Northern blot
Increased
3
Korc et al. 1992
Invasive ductal adenocarcinoma In situ hybridization
Increased
Korc et al. 1992
Invasive ductal adenocarcinoma RT-PCR
Increased
Kolb et al. 2006
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Pancreatic tubular adenocarcinoma Immunohistochemistry
Increased
Ozaki et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Pryczynicz et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Korc et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Gansauge et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Zhang et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Ueda et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Poch et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Zhao et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Ortiz-Zapater et al.
Pancreatic intraepithelial neoplasia Immunohistochemistry
Increased
Ortiz-Zapater et al.
Invasive ductal adenocarcinoma Western blot
Increased
10.6
Korc et al.
Pancreatic ductal adenocarcinoma Immunohistochemistry
Increased
Liu et al. 2012
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
BxPC3 Western blot
Increased
Ortiz-Zapater et al. 2007
HPDE Western blot
Increased
Ortiz-Zapater et al. 2007
SK-PC-1 Western blot
Increased
Ortiz-Zapater et al. 2007
PANC-1 Western blot
Increased
Ortiz-Zapater et al. 2007
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
Protein Immunohistochemistry
Increased
Zhao et al.
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."