Pancreatic Cancer Database

Mucin 5AC, oligomeric mucus/gel-forming

Gene Symbol

MUC5AC

Chromosome Locus

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Intraductal papillary mucinous neoplasms	DNA microarray	Increased	149.7	Sato et al. 2004
Intraductal papillary mucinous neoplasms	In situ hybridization	Increased		Yonezawa et al. 1999
Invasive ductal adenocarcinoma	In situ hybridization	Increased		Yonezawa et al. 1999
Invasive ductal adenocarcinoma	DNA microarray	Increased	20.4	Friess et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	3	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	2.6	Grutzmann et al. 2003
Invasive ductal adenocarcinoma	RT-PCR	Increased		Ohuchida et al. 2005
Invasive ductal adenocarcinoma	DNA microarray	Increased	4	Lowe et al. 2007

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
Capan-1	RT-PCR	Increased		Ohuchida et al. 2005
HS766T	RT-PCR	Increased		Ohuchida et al. 2005
H48N	RT-PCR	Increased		Ohuchida et al. 2005
CFPAC	RT-PCR	Increased		Ohuchida et al. 2005
Capan-2	RT-PCR	Increased		Ohuchida et al. 2005
BxPC3	RT-PCR	Increased		Ohuchida et al. 2005
KP-1N	RT-PCR	Increased		Ohuchida et al. 2005
SW1990	RT-PCR	Increased		Ohuchida et al. 2005
Suit-2	RT-PCR	Increased		Ohuchida et al. 2005
Panc-1	RT-PCR	Increased		Ohuchida et al. 2005

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Intraductal papillary mucinous neoplasms	Immunohistochemistry	Increased		Ban et al.
Intraductal papillary mucinous neoplasms	Immunohistochemistry	Increased		Kanno et al.
Intraductal papillary mucinous neoplasms	Immunohistochemistry	Increased		Luttges et al.
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma	Immunohistochemistry	Increased		Luttges et al.
Intraductal oncocytic papillary neoplasm	Immunohistochemistry	Increased		Luttges et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Luttges et al.
Coll	Immunohistochemistry	Increased		Luttges et al.
Intraductal papillary mucinous neoplasms	Immunohistochemistry	Increased		Terada et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Terada et al.
Mucinous cystic neoplasms	Immunohistochemistry	Increased		Terada et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Iacobuzio-Donahue et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Ohuchida et al.
Mucinous cystic neoplasms	Immunohistochemistry	Increased		Luttges et al.
PanIN-1A	Immunohistochemistry	Increased		Maitra et al.
PanIN-1B	Immunohistochemistry	Increased		Maitra et al.
PanIN-2	Immunohistochemistry	Increased		Maitra et al.
PanIN-3	Immunohistochemistry	Increased		Maitra et al.
PanIN-1A	Immunohistochemistry	Increased		Sanada et al.
PanIN-1B	Immunohistochemistry	Increased		Sanada et al.
PanIN-2	Immunohistochemistry	Increased		Sanada et al.
PanIN-3	Immunohistochemistry	Increased		Sanada et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Sanada et al.
Pancreatic ductal adenocarcinoma	Immunohistochemistry	Increased		Matsuyama et al. 2011

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
RNA	DNA microarray	Increased	3.2	Friess et al.

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."