Mucin 1, cell surface associated
Gene Symbol   MUC1 Chromosome Locus   1q21
 
  Alternate Names    
     
 
MAM6; Mucin; MUC1/ZD
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Intraductal papillary mucinous neoplasms DNA microarray
Increased
12.3
Sato et al. 2004
Invasive ductal adenocarcinoma RT-PCR
Increased
Ohuchida et al. 2005
Invasive ductal adenocarcinoma SAGE
Increased
Hustinx et al. 2004
Invasive ductal adenocarcinoma RT-PCR
Increased
Andrianifahanana et al. 2001
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
Capan 1 RT-PCR
Increased
Andrianifahanana et al. 2001
Capan 2 RT-PCR
Increased
Andrianifahanana et al. 2001
HPAF RT-PCR
Increased
Andrianifahanana et al. 2001
ASPC-1 RT-PCR
Increased
Andrianifahanana et al. 2001
HCG25 RT-PCR
Increased
Andrianifahanana et al. 2001
T3M4 RT-PCR
Increased
Andrianifahanana et al. 2001
Colo357 RT-PCR
Increased
Andrianifahanana et al. 2001
BxPC3 RT-PCR
Increased
Andrianifahanana et al. 2001
HPAC RT-PCR
Increased
Andrianifahanana et al. 2001
AsPC1 RT-PCR
Increased
Hustinx et al. 2004
PL11 RT-PCR
Increased
Hustinx et al. 2004
MiaPaCa2 RT-PCR
Increased
Hustinx et al. 2004
BXPC3 RT-PCR
Increased
Hustinx et al. 2004
CFPAC1 RT-PCR
Increased
Hustinx et al. 2004
PL13 RT-PCR
Increased
Hustinx et al. 2004
PL3 RT-PCR
Increased
Hustinx et al. 2004
CAPAN2 RT-PCR
Increased
Hustinx et al. 2004
PL6 RT-PCR
Increased
Hustinx et al. 2004
PL4 RT-PCR
Increased
Hustinx et al. 2004
Hs766T RT-PCR
Increased
Hustinx et al. 2004
Panc1 RT-PCR
Increased
Hustinx et al. 2004
PL12 RT-PCR
Increased
Hustinx et al. 2004
Su8697 RT-PCR
Increased
Hustinx et al. 2004
AsPC1 SAGE
Increased
Hustinx et al. 2004
PL11 SAGE
Increased
Hustinx et al. 2004
MiaPaCa2 SAGE
Increased
Hustinx et al. 2004
BXPC3 SAGE
Increased
Hustinx et al. 2004
CFPAC1 SAGE
Increased
Hustinx et al. 2004
PL13 SAGE
Increased
Hustinx et al. 2004
PL3 SAGE
Increased
Hustinx et al. 2004
CAPAN2 SAGE
Increased
Hustinx et al. 2004
PL6 SAGE
Increased
Hustinx et al. 2004
PL4 SAGE
Increased
Hustinx et al. 2004
Hs766T SAGE
Increased
Hustinx et al. 2004
Panc1 SAGE
Increased
Hustinx et al. 2004
PL12 SAGE
Increased
Hustinx et al. 2004
Su8698 SAGE
Increased
Hustinx et al. 2004
ASPC-1 RT-PCR
Increased
Ohuchida et al. 2005
BxPC-3 RT-PCR
Increased
Ohuchida et al. 2005
KP-1N RT-PCR
Increased
Ohuchida et al. 2005
KP-2 RT-PCR
Increased
Ohuchida et al. 2005
KP-3 RT-PCR
Increased
Ohuchida et al. 2005
Panc-1 RT-PCR
Increased
Ohuchida et al. 2005
MIA PaCa-2 RT-PCR
Increased
Ohuchida et al. 2005
NOR-P1 RT-PCR
Increased
Ohuchida et al. 2005
Capan-1 RT-PCR
Increased
Ohuchida et al. 2005
Capan-2 RT-PCR
Increased
Ohuchida et al. 2005
CFPAC-1 RT-PCR
Increased
Ohuchida et al. 2005
H48N RT-PCR
Increased
Ohuchida et al. 2005
HS766T RT-PCR
Increased
Ohuchida et al. 2005
SW1990 RT-PCR
Increased
Ohuchida et al. 2005
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma Array-based sandwich assay
Increased
Yue et al.
Anaplastic Immunohistochemistry
Increased
Pan et al.
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma Immunohistochemistry
Increased
Luttges et al.
Intraductal oncocytic papillary neoplasm Immunohistochemistry
Increased
Luttges et al.
Colloid (mucinous noncystic) adenocarcinoma Immunohistochemistry
Increased
Luttges et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Luttges et al.
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma Immunohistochemistry
Increased
Luttges et al.
Intraductal oncocytic papillary neoplasm Immunohistochemistry
Increased
Luttges et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Luttges et al.
Colloid (mucinous noncystic) adenocarcinoma Immunohistochemistry
Increased
Luttges et al.
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma Immunohistochemistry
Increased
Suda et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Suda et al.
Intraductal papillary mucinous neoplasm with low-grade dysplasia Immunohistochemistry
Increased
Moriya et al.
Intraductal papillary mucinous neoplasm with high-grade dysplasia (carcinoma in situ) Immunohistochemistry
Increased
Moriya et al.
PanIN-1A Immunohistochemistry
Increased
Moriya et al.
PanIN-1B Immunohistochemistry
Increased
Moriya et al.
PanIN-2 Immunohistochemistry
Increased
Moriya et al.
PanIN-3 Immunohistochemistry
Increased
Moriya et al.
Invasive Immunohistochemistry
Increased
Moriya et al.
Intraductal papillary mucinous neoplasms Immunohistochemistry
Increased
Gold et al.
PanIN-1A Immunohistochemistry
Increased
Gold et al.
PanIN-1B Immunohistochemistry
Increased
Gold et al.
PanIN-2 Immunohistochemistry
Increased
Gold et al.
PanIN-3 Immunohistochemistry
Increased
Gold et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Gold et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Chhieng et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Saitou et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Ohuchida et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Qu et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Tajiri et al.
Tubular adenocarcinoma Immunohistochemistry
Increased
Tajiri et al.
Mucinous cystic neoplasms Immunohistochemistry
Increased
Pan et al.
Mucinous cystic neoplasm with an associated invasive carcinoma Immunohistochemistry
Increased
Luttges et al.
Other Immunohistochemistry
Increased
Garcia et al.
PanIN-1A Immunohistochemistry
Increased
Abe et al.
PanIN-1B Immunohistochemistry
Increased
Abe et al.
PanIN-2 Immunohistochemistry
Increased
Abe et al.
PanIN-3 Immunohistochemistry
Increased
Abe et al.
PanIN-1A Immunohistochemistry
Increased
Maitra et al.
PanIN-1B Immunohistochemistry
Increased
Maitra et al.
PanIN-2 Immunohistochemistry
Increased
Maitra et al.
PanIN-3 Immunohistochemistry
Increased
Maitra et al.
Microcystic serous cystadenoma Immunohistochemistry
Increased
Kosmahl et al.
von Hippel-Landau -associated serous cystic neoplasm Immunohistochemistry
Increased
Kosmahl et al.
Solid serous Adenoma Immunohistochemistry
Increased
Kosmahl et al.
Serous cystadenocarcinoma Immunohistochemistry
Increased
Kosmahl et al.
Pancreatic ductal adenocarcinoma Immunohistochemistry
Increased
Matsuyama et al. 2011
Acinar cell carcinoma Immunohistochemistry
Increased
Fabre et al. 2001
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
CAPAN-1 Immunohistochemistry
Increased
Qu et al. 2004
CFPAC-1 Immunohistochemistry
Increased
Qu et al. 2004
PANC-1 Immunohistochemistry
Increased
Qu et al. 2004
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted
Body Fluid
Serum Yue et al.
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."