Pancreatic Cancer Database

Sperm associated antigen 1

Gene Symbol

SPAG1

Chromosome Locus

8q22.2

Alternate Names

SP75; TPIS; HSD-3.8

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	RT-PCR	Increased		Neesse et al. 2006

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
Panc1	Northern blot	Increased		Neesse et al. 2006
A818-4	Northern blot	Increased		Neesse et al. 2006
HPAF-II	Northern blot	Increased		Neesse et al. 2006
MiaPaCa-2	Northern blot	Increased		Neesse et al. 2006
Suit-2	Northern blot	Increased		Neesse et al. 2006
IMIM-PC2	Northern blot	Increased		Neesse et al. 2006
Aspc-1	Northern blot	Increased		Neesse et al. 2006
FA6	Northern blot	Increased		Neesse et al. 2006
MDAPanc3	Northern blot	Increased		Neesse et al. 2006
T3M4	Northern blot	Increased		Neesse et al. 2006

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
PanIN-1A	Immunohistochemistry	Increased		Neesse et al.
PanIN-1B	Immunohistochemistry	Increased		Neesse et al.
PanIN-2	Immunohistochemistry	Increased		Neesse et al.
PanIN-3	Immunohistochemistry	Increased		Neesse et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Neesse et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
Panc1	Western blot	Increased		Neesse et al. 2006
A818-4	Western blot	Increased		Neesse et al. 2006
HPAF-II	Western blot	Increased		Neesse et al. 2006
MiaPaCa-2	Western blot	Increased		Neesse et al. 2006
Suit-2	Western blot	Increased		Neesse et al. 2006
IMIM-PC2	Western blot	Increased		Neesse et al. 2006
Aspc-1	Western blot	Increased		Neesse et al. 2006
HPDE	Western blot	Increased		Neesse et al. 2006

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

-

Secreted

-

Body Fluid

-

External Links

HPRD	Entrez Gene	OMIM	HGNC
04548	6674	603395	HGNC:11212

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."