Pancreatic Cancer Database

NAD(P)H dehydrogenase, quinone 1

Gene Symbol

NQO1

Chromosome Locus

16q22.1

Alternate Names

DHQU; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:quinone oxireductase

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Increased	5	Nakamura et al. 2004
Invasive ductal adenocarcinoma	DNA microarray	Increased	4.7	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	7.2	Lowe et al. 2007
Invasive ductal adenocarcinoma	DNA microarray	Increased	4.8	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	10	Logsdon et al. 2003
Invasive ductal adenocarcinoma	DNA microarray	Increased	4.7	Grutzmann et al. 2004
PanIN-1A	DNA microarray	Increased	2.4	Prasad et al. 2005
PanIN-1B	DNA microarray	Increased	2.4	Prasad et al. 2005
PanIN-2	DNA microarray	Increased	2.4	Prasad et al. 2005

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
PanIN-1A	Immunohistochemistry	Increased		Sanada et al.
PanIN-1B	Immunohistochemistry	Increased		Sanada et al.
PanIN-2	Immunohistochemistry	Increased		Sanada et al.
PanIN-3	Immunohistochemistry	Increased		Sanada et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Sanada et al.

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
00518	1728	125860	HGNC:2874