Claudin 18
Gene Symbol   CLDN18 Chromosome Locus   3q22.3
 
  Alternate Names    
     
 
Claudin 18 isoform 1; Claudin 18 isoform 2
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Intraductal papillary mucinous neoplasms DNA microarray
Increased
25.8
Sato et al. 2004
Invasive ductal adenocarcinoma DNA microarray
Increased
4.8
Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma DNA microarray
Increased
12.9
Lowe et al. 2007
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
PanIN-1A Immunohistochemistry
Increased
Karanjawala et al.
PanIN-1B Immunohistochemistry
Increased
Karanjawala et al.
PanIN-2 Immunohistochemistry
Increased
Karanjawala et al.
PanIN-3 Immunohistochemistry
Increased
Karanjawala et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Karanjawala et al.
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."