Cyclin-dependent kinase 4
Gene Symbol   CDK4 Chromosome Locus   12q14
 
  Alternate Names    
     
 
Cell division kinase 4; PSK J3
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Intraductal papillary mucinous neoplasms DNA microarray
Increased
5.2
Sato et al. 2004
Invasive ductal adenocarcinoma SAGE
Increased
Hustinx et al. 2004
pancreatic neuroendocrine tumors qRT-PCR
Increased
Tang et al. 2012
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
PanIN-1A Immunohistochemistry
Increased
Al-Aynati et al.
PanIN-1B Immunohistochemistry
Increased
Al-Aynati et al.
PanIN-2 Immunohistochemistry
Increased
Al-Aynati et al.
PanIN-3 Immunohistochemistry
Increased
Al-Aynati et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Al-Aynati et al.
pancreatic neuroendocrine tumors Immunohistochemistry
Increased
Tang et al. 2012
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."