Neuropilin 1
Gene Symbol   NRP1 Chromosome Locus   10p12
 
  Alternate Names    
     
 
Vascular endothelial growth factor 165 receptor; VEGF165R; RP11-342D11.1
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma RT-PCR
Increased
22
Fukahi et al. 2004
Invasive ductal adenocarcinoma SAGE
Increased
Hansel et al. 2004
Invasive ductal adenocarcinoma RT-PCR
Increased
2
Muller et al. 2007
Poorly differentiated endocrine carcinoma RT-PCR
Increased
2
Muller et al. 2007
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
CFPAC-1 Northern blot
Increased
Parikh et al. 2003
Panc-1 Northern blot
Increased
Parikh et al. 2003
Panc-48 Northern blot
Increased
Parikh et al. 2003
ASPC-1 Northern blot
Increased
Parikh et al. 2003
SG Northern blot
Increased
Parikh et al. 2003
L3.6pl Northern blot
Increased
Parikh et al. 2003
HPAF-2 Northern blot
Increased
Parikh et al. 2003
ASPC-1 RT-PCR
Increased
Fukahi et al. 2004
CAPAN-1 RT-PCR
Increased
Fukahi et al. 2004
PANC-1 RT-PCR
Increased
Fukahi et al. 2004
SU8686 RT-PCR
Increased
Muller et al. 2007
Panc1 RT-PCR
Increased
Muller et al. 2007
AsPc1 RT-PCR
Increased
Muller et al. 2007
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Fukahi et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Parikh et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Hansel et al.
Endocrine Neoplasms Immunohistochemistry
Increased
Hansel et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Muller et al.
Pancreatic ductal adenocarcinoma Immunohistochemistry
Increased
Huang et al. 2012
pancreatic intraepithelial neoplasia Immunohistochemistry
Increased
Huang et al. 2012
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
ASPC-1 Western blot
Increased
Fukahi et al. 2004
CAPAN-1 Western blot
Increased
Fukahi et al. 2004
BxPC3 Western blot
Increased
Hansel et al. 2004
PancI Western blot
Increased
Hansel et al. 2004
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."