Matrix metallopeptidase 14 (membrane-inserted)
Gene Symbol   MMP14 Chromosome Locus   14q11-q12
 
  Alternate Names    
     
 
Membrane type matrix metalloproteinase 1; MT1 MMP
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma In situ hybridization
Increased
Bramhall et al. 1997
Invasive ductal adenocarcinoma DNA microarray
Increased
7.3
Iacobuzio-Donahue et al. 2002
Invasive ductal adenocarcinoma DNA microarray
Increased
5.3
Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma DNA microarray
Increased
10
Lowe et al. 2007
Invasive ductal adenocarcinoma In situ hybridization
Increased
Ellenrieder et al. 1999
Invasive ductal adenocarcinoma In situ hybridization
Increased
Ellenrieder et al. 1999
Invasive ductal adenocarcinoma Northern blot
Increased
Ellenrieder et al. 1999
Invasive ductal adenocarcinoma In situ hybridization
Increased
Iacobuzio-Donahue et al. 2002
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
CAPAN-1 Northern blot
Increased
Ellenrieder et al. 1999
CAPAN-2 Northern blot
Increased
Ellenrieder et al. 1999
PANC-1 Northern blot
Increased
Ellenrieder et al. 1999
IMIM-PC2 Northern blot
Increased
Ellenrieder et al. 1999
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Ellenrieder et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Ellenrieder et al.
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."