Matrix metallopeptidase 11 (stromelysin 3)
Gene Symbol   MMP11 Chromosome Locus   22q11.2;22q11.23
 
  Alternate Names    
     
 
MMP 11; Stromelysin 3; STMY3
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma DNA microarray
Increased
3.3
Grutzmann et al. 2004
Invasive ductal adenocarcinoma DNA microarray
Increased
7.2
Laurell et al. 2006
Invasive ductal adenocarcinoma DNA microarray
Increased
3
Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma In situ hybridization
Increased
Iacobuzio-Donahue et al. 2002
Invasive ductal adenocarcinoma DNA microarray
Increased
6.7
Pfeffer et al. 2004
Invasive ductal adenocarcinoma DNA microarray
Increased
17.9
Lowe et al. 2007
Invasive ductal adenocarcinoma SAGE
Increased
Hustinx et al. 2004
Invasive ductal adenocarcinoma Northern blot
Increased
Bramhall et al. 1997
Invasive ductal adenocarcinoma DNA microarray
Increased
5
Crnogorac-Jurcevic et al. 2003
Invasive ductal adenocarcinoma DNA microarray
Increased
5
Nakamura et al. 2004
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
AsPC1 SAGE
Increased
Hustinx et al. 2004
PL11 SAGE
Increased
Hustinx et al. 2004
MiaPaCa2 SAGE
Increased
Hustinx et al. 2004
BXPC3 SAGE
Increased
Hustinx et al. 2004
CFPAC1 SAGE
Increased
Hustinx et al. 2004
PL13 SAGE
Increased
Hustinx et al. 2004
PL3 SAGE
Increased
Hustinx et al. 2004
CAPAN2 SAGE
Increased
Hustinx et al. 2004
PL6 SAGE
Increased
Hustinx et al. 2004
PL4 SAGE
Increased
Hustinx et al. 2004
Hs766T SAGE
Increased
Hustinx et al. 2004
Panc1 SAGE
Increased
Hustinx et al. 2004
PL12 SAGE
Increased
Hustinx et al. 2004
Su8694 SAGE
Increased
Hustinx et al. 2004
AsPc1 Northern blot
Increased
von et al. 1998
Dan-G Northern blot
Increased
von et al. 1998
Capan 1 Northern blot
Increased
von et al. 1998
Capan 2 Northern blot
Increased
von et al. 1998
Panc-1 Northern blot
Increased
von et al. 1998
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Grutzmann et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
von et al.
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
AsPc1 Western blot
Increased
von et al. 1998
Dan-G Western blot
Increased
von et al. 1998
Capan 1 Western blot
Increased
von et al. 1998
Capan 2 Western blot
Increased
von et al. 1998
Panc-1 Western blot
Increased
von et al. 1998
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."