Pancreatic Cancer Database

Fas ligand (TNF superfamily, member 6)

Gene Symbol

FASLG

Chromosome Locus

1q23

Alternate Names

FS-7 and FL associated cell surface antigen; Tumor necrosis factor ligand superfamily, member 6; TNFSF6

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	RT-PCR	Increased		Satoh et al. 1999

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
PANC-1	RT-PCR	Increased		Satoh et al. 1999
ASPC- 1	RT-PCR	Increased		Satoh et al. 1999
BxPC-3	RT-PCR	Increased		Satoh et al. 1999
MIA PaCa-2	RT-PCR	Increased		Satoh et al. 1999
AsPCI	RT-PCR	Increased		Ungefroren et al. 1998
BxPC3	RT-PCR	Increased		Ungefroren et al. 1998
A818-1	RT-PCR	Increased		Ungefroren et al. 1998
Capan-2	RT-PCR	Increased		Ungefroren et al. 1998
Panc89	RT-PCR	Increased		Ungefroren et al. 1998
PancTul	RT-PCR	Increased		Ungefroren et al. 1998
	RT-PCR	Increased		Ungefroren et al. 1998

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Ungefroren et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Kornmann et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Satoh et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Boltze et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
ASPC-1	Western blot	Increased		Kornmann et al. 2000
CAPAN-1	Western blot	Increased		Kornmann et al. 2000
COLO-357	Western blot	Increased		Kornmann et al. 2000
MIA PaCa-2	Western blot	Increased		Kornmann et al. 2000
AsPCI	Western blot	Increased		Ungefroren et al. 1998
BxPC3	Western blot	Increased		Ungefroren et al. 1998
A818-1	Western blot	Increased		Ungefroren et al. 1998
Capan-2	Western blot	Increased		Ungefroren et al. 1998
Panc89	Western blot	Increased		Ungefroren et al. 1998
PancTul	Western blot	Increased		Ungefroren et al. 1998
	Western blot	Increased		Ungefroren et al. 1998
AsPCI	FACS	Increased		Ungefroren et al. 1998
BxPC3	FACS	Increased		Ungefroren et al. 1998
A818-1	FACS	Increased		Ungefroren et al. 1998
Colo357	FACS	Increased		Ungefroren et al. 1998
Panc89	FACS	Increased		Ungefroren et al. 1998
PancTul	FACS	Increased		Ungefroren et al. 1998
	FACS	Increased		Ungefroren et al. 1998
PancTul	Immunohistochemistry	Increased		Ungefroren et al. 1998
Capan2	Immunohistochemistry	Increased		Ungefroren et al. 1998

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

-

Secreted

-

Body Fluid

-

External Links

HPRD	Entrez Gene	OMIM	HGNC
00610	356	134638	HGNC:11936

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."