CD74 molecule, major histocompatibility complex, class II invariant chain
Gene Symbol   CD74 Chromosome Locus   5q32
 
  Alternate Names    
     
 
CD74 antigen isoform c; CD74 antigen isoform a; CD74 antigen isoform b
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma DNA microarray
Increased
4.9
Sato et al. 2004
Invasive ductal adenocarcinoma SAGE
Increased
Hustinx et al. 2004
Invasive ductal adenocarcinoma DNA microarray
Increased
8
Laurell et al. 2006
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
Capan-1 RT-PCR
Increased
Koide et al. 2006
Capan-2 RT-PCR
Increased
Koide et al. 2006
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Koide et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Hustinx et al.
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
Capan-1 Western blot
Increased
Koide et al. 2006
Capan-2 Western blot
Increased
Koide et al. 2006
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
RNA DNA microarray
Increased
2
Binkley et al. 2004
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."