Claudin 4
Gene Symbol   CLDN4 Chromosome Locus   7q11.23
 
  Alternate Names    
     
 
Clostridium perfringens enterotoxin receptor 1; CPETR1; CPER
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma DNA microarray
Increased
5.1
Sato et al. 2004
Intraductal papillary mucinous neoplasms DNA microarray
Increased
10.1
Terris et al. 2002
Invasive ductal adenocarcinoma DNA microarray
Increased
3.6
Lowe et al. 2007
Invasive ductal adenocarcinoma Northern blot
Increased
Michl et al. 2001
Invasive ductal adenocarcinoma SAGE
Increased
Terris et al. 2002
Invasive ductal adenocarcinoma SAGE
Increased
Ryu et al. 2002
Invasive ductal adenocarcinoma DNA microarray
Increased
2.1
Buchholz et al. 2005
Invasive ductal adenocarcinoma DNA microarray
Increased
3.2
Iacobuzio-Donahue et al. 2003
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
PANC-1 Northern blot
Increased
Michl et al. 2001
Capan-1 Northern blot
Increased
Michl et al. 2001
Capan-2 Northern blot
Increased
Michl et al. 2001
MiaPaCa-2 Northern blot
Increased
Michl et al. 2001
Patu8988s Northern blot
Increased
Michl et al. 2001
Patu8988t Northern blot
Increased
Michl et al. 2001
IMIM-PC1 Northern blot
Increased
Michl et al. 2001
IMIM-PC2 Northern blot
Increased
Michl et al. 2001
AsPc1 SAGE
Increased
Ryu et al. 2002
CAPAN1 SAGE
Increased
Ryu et al. 2002
CAPAN2 SAGE
Increased
Ryu et al. 2002
Panc-1 SAGE
Increased
Ryu et al. 2002
PL45 SAGE
Increased
Ryu et al. 2002
AsPc1 RT-PCR
Increased
Iacobuzio-Donahue et al. 2003
BxPc3 RT-PCR
Increased
Iacobuzio-Donahue et al. 2003
CAPAN1 RT-PCR
Increased
Iacobuzio-Donahue et al. 2003
CAPAN2 RT-PCR
Increased
Iacobuzio-Donahue et al. 2003
CFPAC1 RT-PCR
Increased
Iacobuzio-Donahue et al. 2003
Hs766T RT-PCR
Increased
Iacobuzio-Donahue et al. 2003
MiaPaca2 RT-PCR
Increased
Iacobuzio-Donahue et al. 2003
Panc-1 RT-PCR
Increased
Iacobuzio-Donahue et al. 2003
Su86.86 RT-PCR
Increased
Iacobuzio-Donahue et al. 2003
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma Immunohistochemistry
Increased
Sato et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Michl et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Nichols et al.
Pancreatic intraepithelial neoplasia Immunohistochemistry
Increased
Nichols et al.
Pancreatic ductal adenocarcinoma Immunohistochemistry
Increased
Tsutsumi et al. 2011
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."