Pancreatic Cancer Database

Coactosin-like 1 (Dictyostelium)

Gene Symbol

COTL1

Chromosome Locus

16q24.1

Alternate Names

CLP

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Increased	6.3	Iacobuzio-Donahue et al. 2003

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
CFPAC-1	RT-PCR	Increased		Nakatsura et al. 2001
Capan-2	RT-PCR	Increased		Nakatsura et al. 2001
BxPC-3	RT-PCR	Increased		Nakatsura et al. 2001
SUIT-2	RT-PCR	Increased		Nakatsura et al. 2001
MIA-PaCa-2	RT-PCR	Increased		Nakatsura et al. 2001
PaCa-2	RT-PCR	Increased		Nakatsura et al. 2001
Panc-1	RT-PCR	Increased		Nakatsura et al. 2001
CFPAC-1	Northern blot	Increased		Nakatsura et al. 2001
Panc-1	Northern blot	Increased		Nakatsura et al. 2001
PaCa-2	Northern blot	Increased		Nakatsura et al. 2001
AsPc1	DNA microarray	Increased	10.8	Iacobuzio-Donahue et al. 2003
BxPc3	DNA microarray	Increased	10.8	Iacobuzio-Donahue et al. 2003
CAPAN1	DNA microarray	Increased	10.8	Iacobuzio-Donahue et al. 2003
CAPAN2	DNA microarray	Increased	10.8	Iacobuzio-Donahue et al. 2003
CFPAC1	DNA microarray	Increased	10.8	Iacobuzio-Donahue et al. 2003
Hs766T	DNA microarray	Increased	10.8	Iacobuzio-Donahue et al. 2003
MiaPaca2	DNA microarray	Increased	10.8	Iacobuzio-Donahue et al. 2003
Panc-1	DNA microarray	Increased	10.8	Iacobuzio-Donahue et al. 2003
Su86.86	DNA microarray	Increased	10.8	Iacobuzio-Donahue et al. 2003

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	ICAT	Increased	2.2	Chen et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
Protein	Label free quantitation, Mass spectrometry	Increased	2	Pan et al. 2011
Protein	Label free quantitation, Mass spectrometry	Decreased	2.1	Pan et al. 2011

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

-

Secreted

-

Body Fluid

-

External Links

HPRD	Entrez Gene	OMIM	HGNC
09482	23406	606748	HGNC:18304

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."