Pancreatic Cancer Database

Fas (TNF receptor superfamily, member 6)

Gene Symbol

FAS

Chromosome Locus

10q24.1

Alternate Names

Tumor necrosis factor receptor superfamily, member 6 isoform 4; Tumor necrosis factor receptor superfamily, member 6 isoform 6; Tumor necrosis factor receptor superfamily member 6 isoform 2

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Intraductal papillary mucinous neoplasm with an associated invasive carcinoma	DNA microarray	Increased	4.2	Sato et al. 2004
Invasive ductal adenocarcinoma	Northern blot	Increased	3.6	Kornmann et al. 2000

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
ASPC-1	Northern blot	Increased		Kornmann et al. 2000
CAPAN-1	Northern blot	Increased		Kornmann et al. 2000
COLO-357	Northern blot	Increased		Kornmann et al. 2000
MIA PaCa-2	Northern blot	Increased		Kornmann et al. 2000

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	FACS	Increased		Ungefroren et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Gansauge et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Kornmann et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
ASPC-1	Western blot	Increased		Kornmann et al. 2000
CAPAN-1	Western blot	Increased		Kornmann et al. 2000
COLO-357	Western blot	Increased		Kornmann et al. 2000
MIA PaCa-2	Western blot	Increased		Kornmann et al. 2000

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
00609	355	134637	HGNC:11920

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."