Pancreatic Cancer Database

Cyclin D1

Gene Symbol

CCND1

Chromosome Locus

11q13

Alternate Names

BCL1; Parathyroid adenomatosis 1; PRAD1

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Endocrine Neoplasms	Northern blot	Increased		Guo et al.
Invasive ductal adenocarcinoma	DNA microarray	Increased	3	Iacobuzio-Donahue et al. 2003
Invasive ductal adenocarcinoma	RT-PCR	Increased		Gansauge et al. 1997
Invasive ductal adenocarcinoma	DNA microarray	Increased	2.8	Kristiansen et al. 2006
Well-differentiated pancreatic endocrine neoplasm	Northern blot	Increased		Chung et al. 2000

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Endocrine Neoplasms	Immunohistochemistry	Increased		Guo et al.
Intraductal oncocytic papillary neoplasm	Immunohistochemistry	Increased		Rouzbahman et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Poch et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Gansauge et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Gansauge et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Li et al.
PanIN-2	Immunohistochemistry	Increased		Li et al.
PanIN-2	Immunohistochemistry	Increased		Maitra et al.
PanIN-3	Immunohistochemistry	Increased		Maitra et al.
PanIN-2	Immunohistochemistry	Increased		Biankin et al.
PanIN-3	Immunohistochemistry	Increased		Biankin et al.
Intraductal papillary mucinous neoplasms	Immunohistochemistry	Increased		Biankin et al.
PanIN-2	Immunohistochemistry	Increased		Biankin et al.
PanIN-3	Immunohistochemistry	Increased		Biankin et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Biankin et al.
PanIN-2	Immunohistochemistry	Increased		Al-Aynati et al.
PanIN-3	Immunohistochemistry	Increased		Al-Aynati et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Al-Aynati et al.
Solid-pseudopapillary neoplasm	Immunohistochemistry	Increased		Abraham et al.
Well-differentiated pancreatic endocrine neoplasm	Immunohistochemistry	Increased		Chung et al.
Endocrine Neoplasms	Western blot	Increased		Guo et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
Protein	Immunohistochemistry	Increased		Gansauge et al.

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
01346	595	168461	HGNC:1582