Pancreatic Cancer Database

B-cell CLL/lymphoma 2

Gene Symbol

BCL2

Chromosome Locus

18q21.33;18q21.3

Alternate Names

B-cell lymphoma protein 2 beta isoform; B-cell lymphoma protein 2 alpha isoform; B-cell lymphoma protein 2 alpha

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	In situ hybridization	Increased		Friess et al. 1998
Invasive ductal adenocarcinoma	Northern blot	Increased	6.7	Friess et al. 1998
Invasive ductal adenocarcinoma	RT-PCR	Increased		Sharma et al. 2005
Pancreatic ductal adenocarcinoma	Real-time fluorescence quantitative PCR	Increased		Cao et al. 2012

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Endocrine Neoplasms	Immunohistochemistry	Increased		Wang et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Qiao et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Ohshio et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Virkajarvi et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Wang et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Friess et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Sharma et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Gansauge et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Sun et al.
Pancreatic ductal adenocarcinoma	Immunohistochemistry	Increased		Cao et al. 2012

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
No Data

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
Protein	Immunohistochemistry	Increased		Sun et al.

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
01045	596	151430	HGNC:990