Pancreatic Cancer Database

Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

Gene Symbol

ITGB1

Chromosome Locus

10p11.2

Alternate Names

Very late activation protein, beta polypeptide; VLA beta; VLAB

RNA Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	DNA microarray	Increased	3	Iacobuzio-Donahue et al. 2003
Pancreatic cancer	qRT-PCR	Increased		Zhou et al. 2012
Invasive ductal adenocarcinoma	DNA microarray	Increased	2	Van et al. 2012

Protein Alterations

Cancer Type	Experiment Type	Expression Level	Fold Change	PubMed ID
Invasive ductal adenocarcinoma	ICAT	Increased	2.7	Chen et al.
Invasive ductal adenocarcinoma	Immunocytochemistry	Increased		Chen et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Chen et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Gronborg et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Chen et al.
Invasive ductal adenocarcinoma	Immunohistochemistry	Increased		Gesierich et al.
Invasive ductal adenocarcinoma	Western blot	Increased	2.7	Chen et al.
Invasive ductal adenocarcinoma	Western blot	Increased	2.7	Crnogorac-Jurcevic et al.

Cell Line	Experiment Type	Expression Level	Fold Change	PubMed ID
Panc1	SILAC	Increased	3.4	Gronborg et al. 2005

Chronic Pancreatitis

RNA/Protein	Experiment Type	Expression Level	Fold Change	PubMed ID
Protein	Immunohistochemistry	Increased		Gesierich et al.
Protein	Immunohistochemistry	Increased		Chen et al.
Protein	ICAT	Increased	2	Chen et al.
Protein	Label free quantitation, Mass spectrometry	Increased	2.1	Pan et al. 2011

Expressed in Body Fluid /Plasma Membrane

Plasma Membrane

Secreted

Body Fluid

External Links

HPRD	Entrez Gene	OMIM	HGNC
00628	3688	135630	HGNC:6153