Amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
Gene Symbol   APP Chromosome Locus   21q21.2;21q21.3
 
  Alternate Names    
     
 
CVAP; PN2; ABPP
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Intraductal papillary mucinous neoplasms DNA microarray
Increased
8.6
Sato et al. 2004
Invasive ductal adenocarcinoma DNA microarray
Increased
5.2
Buchholz et al. 2005
Invasive ductal adenocarcinoma DNA microarray
Increased
5
Nakamura et al. 2004
Invasive ductal adenocarcinoma RT-PCR
Increased
Nakamura et al. 2004
PanIN-3 DNA microarray
Increased
2.4
Buchholz et al. 2005
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
Panc1 SILAC
Increased
3
 Gronborg et al. 2005
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
-
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."