Caspase 3, apoptosis-related cysteine peptidase
Gene Symbol   CASP3 Chromosome Locus   4q34
 
  Alternate Names    
     
 
Yama protein; PARP cleavage protease; Cysteine protease CPP32
 
   
 
  RNA Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Intraductal papillary mucinous neoplasm with high-grade dysplasia (carcinoma in situ) RT-PCR
Increased
Satoh et al. 2000
Intraductal papillary mucinous neoplasm with moderate dysplasia RT-PCR
Increased
Satoh et al. 2000
Invasive ductal adenocarcinoma RT-PCR
Increased
Satoh et al. 2000
Invasive ductal adenocarcinoma RT-PCR
Increased
Carbone et al. 2005
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
  Protein Alterations     
     
 
Cancer Type
Experiment Type
Expression Level
Fold Change
PubMed ID
Intraductal papillary mucinous neoplasm with high-grade dysplasia (carcinoma in situ) Immunohistochemistry
Increased
Satoh et al.
Intraductal papillary mucinous neoplasm with moderate dysplasia Immunohistochemistry
Increased
Satoh et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Satoh et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Virkajarvi et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Carbone et al.
Invasive ductal adenocarcinoma Immunohistochemistry
Increased
Meggiato et al.
Pancreatic cancer Western blot
Increased
Schneider et al. 2011
Cell Line
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 Chronic Pancreatitis    
     
 
RNA/Protein
Experiment Type
Expression Level
Fold Change
PubMed ID
No Data
 
   
 
 
  Expressed in Body Fluid /Plasma Membrane  
     
 
     
 
Plasma Membrane -
Secreted - 
Body Fluid
 
   
 
   
 
  External Links     
     
 
HPRD
Entrez Gene
OMIM
HGNC
 
   
 
 
 
 

Pancreatic Cancer Database was funded by the "Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins."